Showing posts with label die. Show all posts
Showing posts with label die. Show all posts

Sunday, November 6, 2011

Buried Alive


Do you have a fear of being buried alive? For me it's probably more of a scary thought than something I truly worry about on a regular basis. But just imagine for a moment waking up and realizing you're in a box several feet underground. There's not much room for you to move around in or adjust your position, you're pretty much stuck there until you die. Any efforts on your part to try to save yourself are really just a waste of energy. And this would probably be the hardest part about it: your body will immediately go into panic mode and you'll start pushing as hard as you can with your hands and trying to kick with your feet. But being in such a tight enclosure and lying on your back, you really don't have enough leverage to really accomplish anything. So which is the best course of action, to keep kicking and pushing for hours until you die? Or to attempt to control your body, to tell yourself to relax, accept your fate, close your eyes and realize there's nothing you can do?

It seems to me that the best option is to try to calm yourself down and lay there peacefully, because the more you try to push yourself out of that position the more frustrated and panicked you're going to become. But it could be that it's simply impossible for most people to just lay there and take it calmly, perhaps our instincts would take over and not listen to our mind telling the body to relax. It would be a struggle not so much to escape, but a struggle to calm the mind and body.

It might seem silly today to think about the prospect of being buried alive but there was a time where it was a real possibility.

From Wikipedia:

Before the advent of modern medicine, the fear was not entirely irrational. Throughout history, there have been numerous cases of people being buried alive by accident. In 1905, the English reformer William Tebb collected accounts of premature burial. He found 219 cases of near live burial, 149 actual live burials, 10 cases of live dissection and 2 cases of awakening while being embalmed
It also mentions that people who could afford it arranged to be buried in a "safety" coffin, which had bells and other means to alert those on the outside they were still alive, along with pipes delivering oxygen. It's a good idea, however wouldn't it just be easier to wait a couple days before burying the body?

Snopes.com has some very sad stories involving premature burial, many of them during epidemics where people were dying left and right from various illnesses.
Some instances were especially heartbreaking. In the 1850s, a young girl visiting Edisto Island, South Carolina, died of diphtheria. She was quickly interred in a local family's mausoleum because it was feared the disease might otherwise spread. When one of the family's sons died in the Civil War, the tomb was opened to admit him. A tiny skeleton was found on the floor just behind the door.


There's an organization "Monochrom: Experience the Experience" which did a project on being buried alive, you could experience it yourself for 15 minutes! Sounds like a blast. More information and pictures here.

Wednesday, March 30, 2011

Compounding Pharmacy "Meds IV" Connected to 9 Deaths

Nine people have died in Atlanta, GA following an IV treatment. And the 9 deaths (19 outbreaks total) spanned across 6 different hospitals, so it isn't an issue with a particular hospital having a contamination or problem not following procedure. The common denominator? They all received a Nutrition IV from "Meds IV", a compounding pharmacy. It was found that the deaths were caused by a bacteria called Serratia marcescens.

from gbp.org:

The Alabama Department of Public Health said it first learned of the problem on March 16, when two hospitals in the state notified officials of patients with bloodstream infections.

The cases of bacteremia were caused by Serratia marcescens, a germ that produces bright bright red colonies. The bacterium was identified and named in Italy in the early 1800s, after it was found to be turning polenta blood-red.
This event will no doubt raise questions about quality control at compounding pharmacies. Unlike most pharmacies, compounding pharmacies make most of the solutions they dispense themselves. This provides a value for patients that require custom made ointments, oral solutions, and IVs. But it does make it more difficult to ensure the dosage and quality. Instead of mass producing thousands of the same pill on a daily basis as a pharmaceutical manufacturer might do which could be more easily monitored and controlled, compounding pharmacies produce their medications only when a particular patient has a need for it. They're made to order. So one minute a pharmacist is making an oral solution, the next minute the same pharmacist could be producing a completely different inhalant powder.

We tried visiting the website of "Meds IV" but it appears they've recently taken the site down in light of the allegations. We were able to view a cached version before it was removed (click on image to view full size):





Their most important asset is their reputation...well, I guess that's all gone to shit. If customer satisfaction is guaranteed, what does that mean if they kill you? Do they bring you back to life?

We're trying to find more information about Meds IV, they don't appear to be that well known with much of a presence. They don't even list an address on their website and a search for their phone number 205-837-0899 turns up nothing.

Update:

We have found the president of Meds IV, Tim Rogers.



click on image to view full size.

There is next to nothing to be found about Meds IV, besides the latest articles. We're guessing this was a very small operation that was fairly new with not a lot of customers. Perhaps he offered the hospitals a steep discount to get his foot in the door. It could be that there are some legal issues with compounding pharmacies selling to hospitals. It is standard practice for a compounding pharmacy to make medications for a particular patient. But when they start producing it in bulk to resell to hospitals and aren't seeing any patients at all, that could be a problem. Instead of being a pharmacy they're getting into manufacturer territory and need to be treated and regulated as such.

Update 2: Was the Parenteral Nutrition I.V. a hard to find item (HTF)?

If you look at the list of products that were displayed on Meds IV's website, you may or may not notice that many of them are items that are in short supply. Heparin and Promethazine for example have had supply issues for quite some time now. It appears that indeed there were supply issues with the parenteral nutrition I.V., from nutritioncare.org:

Parenteral Nutrition Product Shortages

There is a growing and critical shortage of electrolyte and mineral injections needed for parenteral nutrition. We have heard from many consumer groups, healthcare systems, and clinicians regarding their short supplies or inability to obtain these products. The seriousness of this shortage has the potential to be similar to that of intravenous (IV) multivitamins, which resulted in significant complications and some deaths.
Compounding & The Hard-To-Find Market

People Liking People actually have a little experience in the little known hard to find market of hospital pharmaceuticals/I.V.s. Different medications go in short supply all the time. There's only so much supply to go around, and sometimes there's not enough to meet the demand, whether it's a raw material shortage, a legal issue, or manufacturing problem. Well some medications are absolutely vital and when you have a patient dying on a hospital bed, the hospital will try to do whatever they can to find the medication that they need. And they're also willing to pay a lot more for that medication. This sets the stage for the hard to find market.

The hard to find market consists of many distributors that make their money off these shortage problems. They get wind that a product is going to go short, so they stock up as many as they can at the low price from a variety of suppliers and manufacturers. They may either flip them to another distributor for a quick profit, or wait for the market price to quadruple and sell them to hospitals for much higher. It doesn't always go as planned, so there's a lot of guessing and risk/reward calculating going on.

Well for some medications there simply isn't any product left, even the hard to find distributors don't have any. Hospital pharmacists are calling all the suppliers they can think of and no one is able to get their hands on it. This sets the stage for the compounding pharmacy to enter the hard to find market. When the hospitals have run out, their primary wholesaler has run out, the manufacturer isn't able to produce much more, and the hard to find distributors can't get their hands on any, the compounding pharmacist is the only other option in creating availability, and they then take advantage of this situation and sell their compounded product at ridiculously high profit margins. Something that might cost $4 to make could be sold for $1,000.

It appears to us now that this isn't just your average compounding pharmacy that's just helping out and serving hospitals from time to time. It may be that their whole business revolves around these shortages. Not that that's necessarily an evil business model, but like I said before when you start compounding on a massive scale you go from compounder to manufacturer. And I'm willing to bet that Tim Rogers and whoever else ran Meds IV just wasn't up to the task. Every week they're probably making something new that the week before hadn't even heard of. It's short? Ok let's make it. They don't specialize in a group of particular meds, they switch between what's selling and what's not at the blink of an eye. So if that's truly the model it's no wonder that their quality control wasn't exactly up to par.